Meibomian Gland Dysfunction in Primary and Secondary Sjögren Syndrome

Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome

PURPOSE To assess the tear film and meibomian gland (MG) features in a Norwegian cohort of patients with primary Sjögren´s syndrome (pSS) and in age- and gender-matched control subjects. METHODS Thirty-four female patients with pSS (age 52.9±11.9 years) and 32 female control subjects (age 49.0±11.5 years) were recruited. After completion of Ocular Surface Disease Index (OSDI) questionnaire an...

Meibomian gland dysfunction

Meibomian gland dysfunction.

Blepharitis is probably the most common disease entity seen in the general ophthalmologist's office. A significant proportion of these cases are secondary to meibomian gland disease. This review outlines our knowledge of the histopathology, lipid abnormalities and role of microorganisms in meibomian gland dysfunction. We will also review the physiology of meibomian gland secretion and present m...

Meibomian Gland Dysfunction and Hypercholesterolemia

High cholesterol is a known risk factor for ischemic heart, cerebrovascular, and peripheral vascular disease. Previous studies have postulated that hypercholesterolemia (defined as total cholesterol of at least 200 mg/dL) also plays a role in the development of meibomian gland dysfunction (MGD). In this observational, case-control study, Pinna et al. investigated the correlation between MGD and...

Meibomian Gland Dysfunction: Endocrine Aspects

Purpose. To compare the hormone levels of patients with seborrheic meibomian gland dysfunction with controls. Procedures. This is a retrospective case-control study involving 50 patients and 50 controls. Blood workup for hormones was studied in both groups by using macroELISA (enzyme-linked immunosorbent assay). Statistical evaluation was done by using SPSS 15.0 independent samples t-test. Resu...